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109 Trans-sphenoidal surgery is not without complications, including death, stroke, hemorrhage, visual loss, meningitis, cerebrospinal fluid rhinorrhea, ophthalmoplegia, permanent diabetes insipidus, hypopituitarism, and nasal septal perforation. M. Some authors have assayed efficacy against a particular bacterium or fungus, for example Helicobacter pylori 26, Cunninghamel- la echinulata 27, and Botrytis cinerea 28. And Kelly, CT, United States Surgical Corporation, 1988, p.

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